Cefpodoxime

• Coverage beyond compare against key urinary pathogens

• More active than Cefuroxime against Providencia-commonly seen in elderly and catheterized patients
• Significantly higher target tissue concentration than Cefixime provides better clinical efficacy
• Randomised controlled Indian Study: Higher cure rate of Cefpodoxime compared to Cefixime

Clavulanic Acid

• Clavulanic acid has negligible intrinsic antimicrobial activity
• Acts as a competitive inhibitor of beta-lactamases
• Restores the antimicrobial activity of beta-lactam antibiotics